In order to speed up the construction progress of the whole line, it is proposed to add a track-laying base at a long station to be built. Meanwhile, to analyze the safety of the main structure of the station, it is necessary to calculate the anti-floating of the station when the underground water level rises. Based on the field monitoring data, using three-dimensional finite element software, the influence of the main structure floating caused by different underground water level and different opening scope of the roof of subway station is studied. The results show that, without considering the friction resistance between the main structure of the station and the enclosure structure, theamount of buoyancy near the railway track Wells is largeafter the closure of part of the precipitation Wells, and the influence degree of buoyancy is different in different parts of the station, so the anti-buoyancy measures should be considered separately. Under the condition of the same water level rise, the roof opening range and the maximum buoyancy of the main structure of the station show a nonlinear growth relationship. Therefore, different measures should be taken to suppress the buoyancy of the main structure of the station for the track wells, shield Wells and other special equipment wells with different opening ranges.