Unblocked road network is essential for the passage of people and the transportation of rescue resources when facing frequent natural disasters. The research objective is to analyze the seismic resilience change characteristic of urban road network. First, considering the spatial characteristic of earthquake and the comprehensive earthquake damage of road infrastructures, a link connectivity probability model based on intensity attenuation distribution is constructed, thus vulnerable sections are identified. Then, the seismic resilience of specific network under different scenarios is analyzed using a network structural resilience assessment model which considered 3 dimensions. Evaluation results of the effects of these vulnerable links elimination in the network show that network resilience is still strong when a few roads canceled, while this ability is significantly getting poor after the cumulative attack on the other vulnerable sections. Therefore, network transportation efficiency is reduced, and the connection between nodes are weakened. The network topology and simulation results lead to strategies of improving resilience.