Based on cloud computing and power supply information system， this paper reestablished the Ali cloud computing-oriented framework of power supply information system of Shenyang Railway Bureau. Firstly， this paper discussed such problems as system slowness， high pre-construction cost and difficulties in post main- tenance by taking into account the cloud situation of domestic railway industry and by the planning and design of the existing power supply information for the Shenyang Railway Bureau. Then， the second combination of cloud products was carried out to form a hybrid cloud model through comprehensive and in-depth learning of Ali cloud. Finally， the two aspects were combined to form a hybrid cloud information system framework under the cloud environment. This framework may provide railway power supply departments with the cloud platform con- ditions for their efficient and comprehensive administration and production scheduling， representing characteris- tics including large scale， virtualization， high reliability and scalability， which develops a feasibility study on cloud migration of information system.