The natural asphalt has a stable physical and chemical properties, good anti-aging performance and temperature sensitivity thanks to the influence of natural environment for long time. The commonly used 90# base asphalt and two kinds of natural asphalts were selected to prepare the modified asphalt by melt blending method, then the technical properties of natural asphalt modified asphalt were studied. The effects of natural as- phalt on the pavement performance and mechanical properties of the asphalt mixture were studied based on the AC-13 asphalt mixture. The research results show that after adding TLA and rock asphalt, the penetration and ductility of the 90# base asphalt decrease, and the softening point and the viscosity increase. The dynamic sta- bility, the RMS and TSR of asphalt mixture increase, the compressive strength and modulus of resilience of as- phalt mixture increase, which show that the TLA and rock asphalt can improve the anti-rutting performance, wa- ter stability and structural bearing capacity of the asphalt mixture, and with the increase of dosage of the TLA and rock asphalt, the improvement effect is more significant. The results of low temperature bending test show that the low temperature cracking resistance performance of asphalt mixture is decreased after adding TLA and rock asphalt. However, the modified asphalt mixture with 4%, 8% and 12% rock asphalt, and the modified as- phalt mixture with 20% and 30% TLA asphalt are still in accordance with the requirements of the winter cold zone level (greater than 2 300 με).