Based on the civil aviation passenger and cargo transport volume and the output value of high-tech industry in Jiangsu Province in the past 20 years, this paper analyzes the interaction between civil aviation transport industry and high-tech industry through unit root inspection, co-consolidation test, Granger causality and impulse response analysis of VAR model. The result shows that there is an interactive relationship between civil aviation transport industry and high-tech industry in Jiangsu Province, and the high-tech industry has obvious effects on air transport industry, especially air cargo industry. It tries to provide reference for the coordinated development of civil aviation passenger and cargo transportation and industrial economy in Jiangsu Province.