Reinforced concrete(RC) bridge piers and columns located in strong saline soil and salt lake area in western China are suffering from corrosion attack, so a new type of composite column is proposed,which is herein referred to as steel reinforced polyethylene plastic pipe(SRPE) confined reinforced concrete column. Eight SRPE confined reinforced concrete columns and four unconfined control columns subjected to eccentric load were tested to study their mechanical properties.The failure pattern and load-axial displacement curves of specimens were obtained. The influence of design parameters such as pressure level of SRPE pipe, eccentricity and slenderness ratio on the mechanical properties of specimens was analyzed. The calculation formula of ultimate bearing capacity of SRPE pipe confined reinforced concrete columns subjected to eccentric load is also proposed for the actual application reference. The experimental results show that the ultimate bearing capacity and ductility of the RC columns under eccentric load are significantly improved for the confinement by SRPE pipe; The bearing capacity increases with the increase of pressure level of SRPE pipe, but the ductility is improved little. The bearing capacity decreases with the increase of eccentricity and slenderness ratio. The ductility of specimens decreases with the increase of slenderness ratio; The lateral peak deflection in the middle height of column confined by SRPE pipe is much larger than that of the control specimens, which increases with the increase of eccentricity and slenderness ratio; The lateral deflection corresponding to ultimate load is close to sine half-wave curve.