Abstract:A series of PDAAM-co-PNIPAM-co-Mu copolymers were synthesized by RAFT polymerization from diacetone acrylamide (DAAM),N-isopropylacrylamide (NIPAM) and ureidopyrimidinone-containing monomer (Mu). Smart hydrogels crosslinked with acylhydrazone dynamic covalent bonds were obtained by the reaction between PDAAM-co-PNIPAM-co-Mu and adipic dihydrazide(ADH). The structure, mechanical properties and intelligent properties of intelligent hydrogel were investigated by scanning electron microscope (SEM),rheometer and universal testing machine. Due to the introduction of ureidopyrimidinone(UPy) hydrogen-bonding units into the network, the mechanical properties of the hydrogels were reinforced, and the compression strength of the hydrogel was increased by 4 times. Meanwhile, the hydrogels exhibited pH and temperature dual-responsive and self-healing properties, and the compression strength was increased by 30 times after heating.