【Objective】In order to explore the structural vibration and noise characteristics of high-speed railway CRTS Ⅲ type plates and double block tracks.【Method】Based on the method of finite element, multi-body dynamics and boundary element, the dynamic model and boundary element model of high-speed train-ballastless track-box girder coupling system are established to study the structural dynamic response and noise radiation characteristics of the train-track-box girder coupling system.【Result】The results show that the maximum wheel load reduction rate of the train is 0.053 6 and 0.165 7, and the deflection of the lower box girder is 1/9 673 and 1/8 457, respectively, when the train passes the CRTS Ⅲ plate and the double-block track structure section on the bridge. Compared with the double-block ballastless track, the displacement response of the track plate and the base of the CRTS Ⅲ plate is smaller, and the vertical vibration attenuation of the track-box girder system is faster, and the vibration damping performance is better. In addition, the total sound pressure level of the box girder noise of CRTS Ⅲ segment is lower than that of the two types of track structure. However, the difference between the peak noise of the far field point under the bridge is small, and the peak frequency is similar, both of which are about 31.5 Hz. The peak frequency under the bridge has large differences, the peak frequency of type Ⅲ board being 63 Hz, and the double block type being 20 Hz.【Conclusion】CRTS Ⅲ plate type ballastless track is more suitable for use in high-speed railway bridge sections.