Hump shunting is a common way of shunting operations by using the gravity of a vehicle to carry out shunting operations, but derailment accidents often happen at the turnout zone of hump yard. In this paper, a test was designed in hump yard. The horizontal force and vertical force of the 6# ballast in the hump yard were test- ed under the three conditions of the multi-hook slide on the sunny day, the multi-hook slide besides friction control on the rainy day and the entire column slide besides friction control on the rainy day. The influence of marshalling mode on the vehicle derailment coefficient at the turnout zone of hump yard was also analyzed. The research results show that the derailment coefficient of empty vehicles is about 12% higher than that of the load vehicles. The impact of the mixed sequence of empty and load vehicles on empty vehicles and load vehicles are different. The sequence can change the derailment coefficient of load vehicles slightly. The sequence of empty and load vehicles should be selected according to different working conditions. The order of the load vehicles before the empty vehicles can reduce the derailment coefficient of the empty vehicles by 16% under the condi- tion of the friction control on rainy days. The entire column slide mode would greatly improve the derailment co- efficient of vehicles. For load vehicles, it is increased by 41%; for empty vehicles, it is increased by 38%. Then, long marshalling should be avoided. To ensure the safety of the vehicle and the efficiency of marshalling, it is recommended that 8 cars should be thrown each time. For daily maintenance work, the high rail and switch rail at the turnout zone should be paid more attention to.