In order to study the influence of the pier structure on the seismic performance of the high-pier continuous beam bridge, the software Ansys was applied to establish three bridge models with various pier cross sections including solid rectangular thin -walled pier, double -column pier and hollow rectangular thin -walled pier to further analyze the dynamic characteristics and seismic performance of the models. The results show that the response results of the bridge pier under earthquakes of E1 and E2 are the same in the response spectrum analysis: the displacement of double-column pier top is larger than that of rectangular thin-walled pier, and the pier base bending moment is smaller than that of rectangular thin-walled pier. Under uniform excitation, the internal force at the bottom of a hollow rectangular thin -walled pier is smaller than that of a solid rectangular thin-walled pier, but the displacement at the top of the pier is larger; compared with the rectangular thin-walled pier, the internal force at the bottom of the double-pillar pier is smaller and the displacement at the top of the pier is larger. Through response spectrum analysis and consistent excitation analysis, it is found that the doublepillar pier can reduce the internal force response of the whole bridge structure when earthquake occurred which accord with the displacement calculation possessing excellent seismic performance.