The mainstream operation mode of close staggered parallel runways in China is of isolated and parallel operation. Since this mode uses a more conservative wake safety separation, a certain degree of congestion may occur during the relatively concentrated period of aircraft departure. In this regard, the paper selects the dual takeoff and double landing related operation mode, takes the close staggered parallel runways as the research object, combines the evolution characteristics of the takeoff wake, and proposes an aircraft takeoff wake dynamic reduction method based on meteorological conditions. The main parameters of the airport’s runway are the simulation reference conditions, and the simulation verification is carried out by using the built-up wake dynamic reduction simulation system. The simulation results show that the takeoff wake encounter metric based on the roll moment coefficient proposed in the paper is reasonable, and the wake separation can be reduced to less than 100 s.