Based on complex network theory, the route networks of the three major airline alliances (Star Al- liance, SkyTeam, Oneworld) are taken as the research objects. The topological characteristics and robustness of the three alliance networks are compared and analyzed. The results include the following points: the route net- work of Star Alliance radiates the largest number of airport nodes with the largest average degree；the three major alliance networks all have scale-free features and small-world network effects；the robustness of the three al- liance networks is better under random attacks, and weaker under deliberate attacks；no matter underdeliberate or random attacks, the robustness of Star Alliance network is better than that of Sky Team and Oneworld. This study may provide a theoretical basis for the optimization design of alliance route network.